International Journal of Clinical Pediatrics, ISSN 1927-1255 print, 1927-1263 online, Open Access
Article copyright, the authors; Journal compilation copyright, Int J Clin Pediatr and Elmer Press Inc
Journal website http://www.theijcp.org

Original Article

Volume 1, Number 2-3, June 2012, pages 55-62


Febrile Seizures With Pandemic (H1N1) 2009 Virus Infection

Figures

Figure 1.
Figure 1. Age distribution of children with influenza A (H1N1) pdm infection.
Figure 2.
Figure 2. Seasonal distribution of children with influenza A (H1N1) pdm infection.
Figure 3.
Figure 3. Age distribution of FSs in children with influenza A (H1N1) pdm infection.

Tables

Table 1. Characteristics of FSs in children with 2009 H1N1 influenza infection.
 
Pandemic A (H1N1) FS
WBC: white blood cell count; CRP: C-reactive protein.
Total90
Male60 (66.7%)
Age (year; mean ± SD)4.3 ± 2.8
Patients aged ≥ 6 years23 (25.6%)
Body temperature at seizure occurrence (°C; mean ± SD)39.3 ± 0.9
Positive history of seizures in first-degree relatives25 (27.8%)
Time from fever to seizure occurrence
  < 24 h (%)83 (92.2%)
  > 24 h (%)7 (7.8%)
No. of previous febrile seizures
  041 (45.6%)
  125 (27.8%)
  29 (10.0%)
  34 (4.4%)
  41 (1.1%)
  > 43 (3.3%)
  Unknown4 (4.4%)
Seizure manifestation Simple type (%)82 (91.1%)
Seizure durations
  Average (min; mean ± SD)4.8 ± 8.0
  < 5 min68 (75.6%)
  5 - 15 min7 (7.8%)
  15 - 30 min5 (5.6%)
  ≥ 30 min1 (1.1%)
  Unknown9 (10.0%)
Hospitalized patients12 (13.3%)
Age of hospitalized patients (year; mean±SD)4.5 ± 2.5
WBC (µl; mean ± SD)10,520.0 ± 3856.2
CRP (mg/dl; mean ± SD)0.61 ± 0.87
Positive medications (%)31 (34.4%)

 

Table 2. Comparison of children with FSs in influenza A (H1N1) pdm, seasonal influenza, and non-influenza infection.
 
Pandemic A (H1N1) FSSeasonal influenza FSNon-influenza FS
* P < 0.05, significantly different from the corresponding values for the seasonal influenza FS group. ** P < 0.01, significantly different from the corresponding values for the seasonal influenza FS group. † P < 0.05, significantly different from the corresponding values for the non influenza FS group. †† P < 0.01, significantly different from the corresponding values for the non influenza FS group.
Total9080252
Male60 (66.7%)54 (67.5%)154 (61.1%)
Age (year: mean ± SD)4.3 ± 2.8 *, ††3.1 ± 2.22.1 ± 1.9
Patients aged ≥ 6 years23 (25.6%) *, ††9 (11.3%) †11 (4.3%)
Body temperature at seizure occurrence (°C: mean ± SD)39.3 ± 0.939.2 ± 0.739.3 ± 0.7
Positive history of seizures in first-degree relatives25 (27.8%)14 (17.5%)40 (15.9%)
Time from fever to seizure occurrence
   < 24 h (%)83 (92.2%) **56 (70%) ††223 (88.5%)
   > 24 h (%)7 (7.8%) **24 (30%) ††26 (10.3%)
Negative previous FS history (%)41 (45.6%) ††48 (60%)154 (61.1%)
Seizure manifestation: simple type (%)82 (91.1%)67 (83.8%)216 (85.7%)
Seizure duration
Average (mean ± SD) min4.8 ± 8.04.2 ± 6.24.0 ± 6.0
< 5 min68 (75.6%) *, ††70 (87.5%)227 (90.1%)
5 - 15 min7 (7.8%)4 (5.0%)9 (3.6%)
≥ 15 min6 (6.6%)5 (6.3%)12 (4.8%)
Unknown9 (10.0%)1 (1.3%)5 (2.0%)
Hospitalized patients12 (13.3%)7 (8.8%)18 (7.1%)
Age of hospitalized patients4.5 ± 2.52.9 ± 3.32.1 ± 2.8
WBC (µl; mean ± SD)10,520.0 ± 3856.2 †8,056.5 ± 3592.4 ††12,877.5 ± 5771.5
CRP (mg/dl; mean ± SD)0.61 ± 0.870.69 ± 0.820.99 ± 1.23