| International Journal of Clinical Pediatrics, ISSN 1927-1255 print, 1927-1263 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, Int J Clin Pediatr and Elmer Press Inc |
| Journal website http://www.theijcp.org |
Short Communication
Volume 4, Number 4, December 2015, pages 181-183
The Successful Use of Desmopressin With Tranexamic Acid in Children With Mild Type 1 Von Willebrand Disease Who Undergo Circumcision
Table
| ID | DDAVP dose (μg/kg) | Baseline VWD parameters | 1-h post-DDAVP response | 4-h post-DDAVP response | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FVIII:C | VWF:Ag | VWF:RCo | C/Epi | C/ADP | FVIII:C | VWF:Ag | VWF:RCo | C/Epi | C/ADP | C/Epi | C/ADP | ||
| VWF: von Willebrand factor; RCo: Ristocetin cofactor activity; Ag: antigen; FVIII:C: factor VIII coagulant activity; C/Epi: collagen/epinephrine; C/ADP: collagen/adenosine diphosphate. | |||||||||||||
| 1 | 0.2 | 46 | 38 | 32 | 194 | 119 | 168 | 158 | 112 | 124 | 96 | 128 | 100 |
| 2 | 0.24 | 48 | 39 | 31 | 195 | 124 | 168 | 144 | 110 | 118 | 92 | 122 | 110 |
| 3 | 0.3 | 47 | 40 | 36 | 192 | 122 | 198 | 142 | 112 | 98 | 80 | 132 | 92 |
| 4 | 0.26 | 43 | 38 | 30 | 194 | 119 | 158 | 144 | 128 | 90 | 72 | 108 | 88 |
| 5 | 0.25 | 48 | 37 | 32 | 202 | 120 | 178 | 162 | 130 | 88 | 70 | 126 | 94 |
| 6 | 0.3 | 46 | 42 | 31 | 198 | 118 | 198 | 166 | 144 | 92 | 68 | 132 | 98 |