International Journal of Clinical Pediatrics, ISSN 1927-1255 print, 1927-1263 online, Open Access
Article copyright, the authors; Journal compilation copyright, Int J Clin Pediatr and Elmer Press Inc
Journal website http://www.theijcp.org

Original Article

Volume 1, Number 2-3, June 2012, pages 76-81


Clinical, Laboratory and Radiological Predictors of Extension of Oligoarticular Juvenile Idiopathic Arthritis: A Prospective Study

Figure

Figure 1.
Figure 1. A flowchart of study procedure including patients’ enrollment, allocation, follow up and analysis.

Tables

Table 1. Demographic and Clinical characteristics of the study population
 
Persistent oligoarticular JIA group (N=28)Extended oligoarticular JIA group (N=12)p-value
Abbreviations: CHAQ, Childhood Health Assessment Questionnaire (CHAQ)
Age: (years)0.001
  - Mean ± SD7.4 ± 3.110.4 ± 2.1
  - Range4.1 - 10.95.3 - 12.5
Gender0.763
  - Male20/28 (71.4%)8/12 (66.6%)
  - Female (female %)8/28 (28.6%)4/12 (33.3%)
Disease duration (months)0.445
  - Mean ± SD15.7 ± 7.217.7 ± 6.3
  - Range6.3 - 23.46.9 - 23.7
Joint involvement (No & %)
  - Upper limbs3/28 (10.7%)10/12 (83.3%)< 0.0001
  - Lower limbs26/28 (92.8%)6/12 (50%)0.002
  - Bilateral symmetrical4/28 (14.3%)7/12 (58.3)0.004
Functional capacity grade (0 - 4) (Mean ± SD)1.3 ± 1.12.6 ± 1.50.019
Ritchie articular index (Mean ± SD)14.6 ± 6.428.3 ± 10.60.0009
Visual analog scale (cm) (Mean ± SD)4.9 ± 2.27.8 ± 3.80.022
CHAQ, (Mean ± SD)1.07 ± 1.11.9 ± 1.20.042
Iridocyclitis (No & %)1/28 (3.6%)0/12 (0%)0.507

 

Table 2. Laboratory and radiological features of the study population
 
Persistent oligoarticular JIA group (N = 28)Extended oligoarticular JIA group (N = 12)p-value
Abbreviations: ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; ANA, antineuclear antibody; JAO, juxtaarticular osteoprosis
ESR level (mm/hour), (Mean ± SD)33.9 ± 12.155.6 ± 19.70.003
CRP level (mg/L), (Mean ± SD)9.1 ± 4.522.3 ± 10.60.001
Rheumatoid factor positivity (No & %)0/28 (0%)7/12 (58.3)< 0.0001
Anemia (Hb < 11gm %) (No & %)12/28(42.9%)4/12 (33.3%)0.573
ANA positivity (No & %)12/28(42.9%)1/12 (8.3%)0. 033
Radiological changes mainly JAO (No & %)5/28 (17.9%)6/12 (50%)0. 037