International Journal of Clinical Pediatrics, ISSN 1927-1255 print, 1927-1263 online, Open Access
Article copyright, the authors; Journal compilation copyright, Int J Clin Pediatr and Elmer Press Inc
Journal website http://www.theijcp.org

Case Report

Volume 9, Number 2, June 2020, pages 59-63


Hypereosinophilia as a Presenting Symptom of Acute Lymphoblastic Leukemia in a Child

Figure

Figure 1.
Figure 1. Peripheral blood with eosinophils and bone marrow aspiration smear with eosinophils and blast cells.

Table

Table 1. Results of Laboratory Test in Different Time Periods
 
Laboratory tests with normal rangeAt diagnosisOn day 39 of the treatmentOn day 85 of the treatment
WBC: white blood cell; Ery: erythrocyte count; AST: aspartate aminotransferase; ALT: alanine transaminase; ALP: alkaline phosphatase; GGT: gamma-glutamyl transferase; LDH: lactate dehydrogenise; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; PT: prothrombin time; INR: international normalized ratio; aPTT: activated partial thromboplastin time.
WBC (× 109/L) (3.5 - 10.5)58.04.47.8
Lymphocytes (%) (20 - 40)272065
Neutrophils (%) (44 - 76)737533
Eosinophils (%) (0 - 6)6052
Blast cells (%)000
Hemoglobin (g/L) (115 - 160)13098112
Ery (× 1012/L) (3.7 - 5.4)4.23.43.8
Platelets (× 109/L) (130 - 440)136110220
ESR (mm/h) (< 20 mm/h)202012
Reticulocytes (%) (0.5 - 1.4/100 erythrocytes)0.30.60.6
Urea (mmol/L) (1.7 - 8.3)4.29.06.6
Creatinine (µmol/L) (40 - 120)426572
Bilirubin total (µmol/L) (0 - 21)7.347.85.8
Bilirubin direct (µmol/L) (0 - 8)3.437.82.8
Protein total (g/L) (63 - 84)714570
Albumin (g/L) (35 - 50)452740
AST (U/L) (0 - 41)29.51,47432
ALT (U/L) (0 - 42)26.449928
ALP (U/L) (0 - 660)365929300
GGT (U/L) (8 - 35)3056912
LDH (U/L) (200 - 540)7195,900350
Calcium total (mmol/L) (2.16 - 2.62)2.42.22.5
Potassium (mmol/L) ((3.5 - 5.1)3.94.04.2
Chloride (mmol/L) (98 - 107)101.999.0100
Sodium (mmol/L) (135 - 145)145140142
CRP (mg/dL) (0 - 0.6)0.37.40.5
PT (%) (70 - 120)11353110
INR (0.85 - 1.25)0.941.630.9
aPTT (s) (22.1 - 28.1)29.327.025.2
Fibrinogen (mg/dL) (200 - 340)341145220