International Journal of Clinical Pediatrics, ISSN 1927-1255 print, 1927-1263 online, Open Access
Article copyright, the authors; Journal compilation copyright, Int J Clin Pediatr and Elmer Press Inc
Journal website http://www.theijcp.org

Case Report

Volume 9, Number 3, September 2020, pages 77-81


Mycoplasma pneumoniae Infection in a 13-Year-Old Girl With Down’s Syndrome During the COVID-19 Pandemic

Figure

Figure 1.
Figure 1. Chest CT findings in a 13-year-old girl, 7 days after symptoms’ onset. (a) bilateral peripheral patchy ground-glass opacity (red frame), predominant in the left inferior lobe; (b) bilateral hilar lymphadenopathy (pink arrow); (c) pleural effusion (yellow arrow); (d) bronchial wall thickening (blue arrow).

Table

Table 1. Laboratory Findings of the Patient
 
VariablesReference rangeDays after admissionOn admission
1331
CK: creatine kinase; RBC: red blood cell count; WBC: white blood cell count; PCO2: partial pressure of carbon dioxide; PO2: partial pressure of oxygen; SO2: oxygen saturation; L. pneumoniae: Legionella pneumoniae; M. pneumoniae: Mycoplasma pneumoniae; S. pneumoniae: Streptococcus pneumoniae; Ag: antigen; IgG: immunoglobin G; IgM: immunoglobin M; PCR: polymerase chain reaction; CMIA: chemiluminescent microparticle immunoassay; IA: immunoassay; COVID-19: coronavirus disease 2019.
C-reactive protein< 5.0 mg/L50.890.355.5
Urea nitrogen15 - 50 mg/dL35372121
Creatinine0.60 - 1.30 mg/dL0.650.650.700.78
Sodium135 - 145 mmol/L137139143137
Potassium3.50 - 5.00 mmol/L4.864.514.053.43
Chloride97 - 107 mmol/L10099105101
Carbon dioxide22.0 - 29.0 mmol/L27.830.427.723.7
Protein total60 - 80 g/L81747172
Bilirubin total< 1.2 mg/dL0.3
CK20 - 180 U/L61
Lactate dehydrogenase< 250 U/L208
Alanine aminotransferase13 - 35 U/L23
Aspartate aminotransferase7 - 35 U/L12
Troponin T< 10< 5
Hemoglobin11.0 - 14.5 g/dL13.511.912.7
Hematocrit36-48%393336
RBC4.03 - 5.29 × 106/µL4.353.574.00
Mean corpuscular volume76.7 - 89.2 fL90.692.791
WBC4.00 - 10.00 × 103/µL7.247.688.52
  Neutrophils1.50 - 5.90 × 103/µL4.946.707.71
  Lymphocytes1.40 - 3.80 × 103/µL1.330.380.34
  Eosinophils0.04 - 0.76 × 103/µL0.270.10.01
  Lymphocytes (%)20.0-50.0%18.44.94
  Neutrophils (%)40.0-70.0%68.187.390.5
Platelets175 - 345 × 103/µL360218238
Venous blood gases
pH7.35 - 7.457.31
PCO241 - 51 mm Hg57
PO230 - 40 mm Hg33
Bicarbonate22 - 28 mmol/L28
Base excess-2.0 - 2.0 mmol/L0.9
SO2 (%)7549.5
Carboxyhemoglobin< 2.0 %0.5
Lactic acid0.5 - 2.2 mmol/L3.2
Microbiology
L. pneumoniae Ag (urine)Negative
M. pneumoniae IgG (CMIA)< 10 AU/mL99.6Negative
M. pneumoniae IgM (CMIA)PositivePositive
M. pneumoniae PCR (nasopharynx)Positive
S. pneumoniae Ag (urine)Negative
COVID-19 IgG (IA)< 1.0 AU/mLNegative
COVID-19 IgM (IA)Negative
COVID-19 PCR (nasopharynx)NegativeNegative