International Journal of Clinical Pediatrics, ISSN 1927-1255 print, 1927-1263 online, Open Access
Article copyright, the authors; Journal compilation copyright, Int J Clin Pediatr and Elmer Press Inc
Journal website http://www.theijcp.org

Original Article

Volume 1, Number 4-5, October 2012, pages 103-108


Clinical, Laboratory, and Ultrasound Characteristics of Knee Involvement in Children With Juvenile Rheumatoid Arthritis

Figure

Figure 1.
Figure 1. Ultrsonographic image of active knee in one patient with JRA.

Tables

Table 1. Clinical Characteristics of all JRA Patients
 
VariableData
Disease duration (months) mean ± SD (range)53.3 ± 17.5 (4 - 103)
JRA subtype
  - polyarticular8/19 (42.1%)
  - oligoarticular8/19 (42.1%)
  - systemic3/19 (15.8%)
Active knee joint patients’ n (%)12/19 (63.1%)
Bilateral clinical knee involvement n (%)5 (26.3%)
Ritchie articular index score, mean ± SD15.2 ± 9.6
Steinbrocker grading system, mean ± SD (grade 0 - 4)2 ± 1.2
Childhood Health Assessment Questionnaire (CHAQ), mean ± SD1.2 ± 1.1
Visual analog scale (0 - 10 cm), mean ± SD3.8 ± 2.4

 

Table 2. Clinical, Laboratory, and Ultrasonography Characteristics of Knee Involvement of JRA Patients
 
VariablePatients with active kneePatients with inactive kneeP value
N = 12N = 7
n = number, ESR = erythrocyte sedimentation rate, CRP= C-reactive protein, ANA = antinuclear antibody, USG = ultrsonography.
Clinical(1) Ritchie articular index score, mean ± SD19.5 ± 5.810.1 ± 4.50.0014
(2) Steinbrocker grading system, mean ± SD3.2 ± 1.21.1 ± 0.70.0002
(3) Childhood Health Assessment Questionnaire (CHAQ), mean ± SD2.2 ± 1.21.1 ± 0.40.0155
(4) Visual analog scale (0 - 10 cm), mean ± SD6.8 ± 3.22.7 ± 1.40.002
Laboratory(1) Complete blood count (CBC)
- Hemoglobin (g/dL), mean ± SD9.4 ± 2.712.6 ± 2.40.0208
- Leucocytosis (n positive) (%)5/12(41.7%)1/7(14.3%)0.2155
- Thrombocytosis (n positive) (%)6/12(50%)2/7 (28.6%)0.3614
(2) ESR (mm/hour), mean ± SD54.5 ± 18.924.3 ± 14.80.0015
(3) CRP level (mg/L), mean ± SD22.7 ± 11.412.6 ± 40.0117
(4) Rheumatoid factor (n positive) (%)5/12(41.7%)2/7 (28.6%)0.5681
(5) ANA (n positive) (%)2/12 (16.7% )2/7 (28.6%)0.5392
Ultra-sonographic(1) USG knee synovial thickness (mm), mean ± SD3.2 ± 1.81.1 ± 0.90.0047
(2) USG knee effusion volume (mL), mean ± SD4.3 ± 2.42.1 ± 0.90.0141