A Child With Acute Liver and Kidney Failure Ongoing Encephalopathy: Effectiveness of Plasmapheresis on Acetaminophen Overdose, A Case Report

Abstract

Acetaminophen (APAP) is a commonly used analgesic and antypiretic medication. APAP-induced liver necrosis has been studied extensively, but extrahepatic manifestations of APAP toxicity are not described well in the literature. Adolescents and young adults may be more prone to renal insufficiency in the setting of APAP overdose; however, the reason for this finding is unclear. Here we report therapeutic misadventure of APAP-associated acute renal and liver failure and effectiveness of plasmapheresis on hepatic encephalopathy.




Int J Clin Pediatr. 2014;3(2):63-65
doi: http://dx.doi.org/10.14740/ijcp143w