Atypical Presentation of a Young Female Patient With Takayasu Arteritis: Case Report and Review of Literature

Divey Manocha, Rahul Anand, Pankaj Mehta, Kuldeep Kumar, Richa Dewan


Takayasu arteritis is a chronic non-specific inflammatory disease mainly involving the aorta and its main branches and is a common cause of reno vascular hypertension among young Asian females. Homocystinurias are a group of seven clinically and biochemically distinct disorders that affect the metabolism of the amino acid methionine. We here by discuss an interesting case of a young lady with past medical history of stroke and tubercular lymphadenopathy who presented with fatigue, chronic abdominal pain and congestive heart failure. Her diagnostic work up revealed multiple manifestations supporting Takayasu arteritis along with history of stroke at young age with co existing marfanoid features. Clinical clues and further diagnostic work up raised the possibility of co- existing Homocysteinuria in our patient.



Takayasu arteritis; Homocystinuria; Hypertension; Congestive heart failure; Cystathionine β-synthase

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International Journal of Clinical Pediatrics, quarterly, ISSN 1927-1255 (print), 1927-1263 (online), published by Elmer Press Inc.                     
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