Non-Cardiogenic Pulmonary Edema With Refractory Hypotension in a Child From Amlodipine Overdoses

Inva Gjeta, Durim Sala, Iliriana Bakalli, Ermela Celaj, Elmira Kola


Intoxications from calcium blockers are not common in daily pediatric practice, but often they can be life-threatening and result fatal for children. Non-cardiogenic edema in children as a result of overdose from amlodipine is rare. In this article, we want to present a case of an intentional intoxication from overdose of amlodipine in a teen girl who suffered complications with refractory hypotension and non-cardiogenic pulmonary edema after 2 days from ingestion. This article wants to highlight the reporting of this rare life-threatening complication because of overdose. It will also focus on the successful supportive treatment with liquids, salt of calcium, vasopressors, glucagon, intra-lipids, mechanical ventilation and the superiority of using high-dose insulin-euglycemia in the concomitant refractory hypotension.

Int J Clin Pediatr. 2020;9(4):120-124


Amlodipine; Non-cardiogenic pulmonary edema; High-dose insulin-euglycemia; Refractory hypotension

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